3. The balance of excitation and inhibition is a pleasant stimulation that nature offers |
KOBAYASHI: Today, neurotransmitters are often an issue even among people involved with children with minor developmental disorders. MOCHIDA: Hyperactivity, for example, is attributed to dysfunction with dopamine, a neurotransmitter in the brain. The balance of neurotransmitters plays a central role in neurological disease: either excess and deficiency of any of the neurotransmitters will result in disorders. KOBAYASHI: Are there more neurotransmitters for triggering postsynaptic excitatory responses? MOCHIDA: Overwhelmingly more, indeed. Mind you, though, that the same neurotransmitter may sometimes trigger excitatory actions and other times inhibitory actions, depending on the context. KOBAYASHI: My guess is that, in our modern society, there are an awful lot of substances that disturb our neurotransmitter balance. MOCHIDA: That's true. If an exogenous element is something easily adhesive to neuroreceptors, or receptors for neurotransmitters, it will certainly affect the associated nerve. For example, many environmental hormones include precisely those elements that are easily attached to neuroreceptors. As a result, excitation that is naturally generated under normal conditions may sometimes be activated by abnormal conditions or substances. KOBAYASHI: Children in today's society, if they miss natural stimulation, may easily resort to artificial stimulation from man-made gadgets or table luxuries, just as adults do. MOCHIDA: If you are just talking about the physical mechanism, that's true. Suppose you only use certain nerves, leaving the rest unused. Then, you can easily drive your nerves into a manic state by taking something like alcohol. But that's the wrong way. We were born and grew up in the beautiful Nature the earth offers, so we'd better activate our nerves through natural stimulation, if we want to be true to real human nature. |