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Mother's Immune Antibody to Protect Her Child - 1

The immune function1 of a newborn to protect his body from viruses has not well developed yet. However, he is usually born with the prototype of the immune function acquired in the process of human evolution unless he suffers from diseases like immunodeficiency syndrome.
For example, it takes three to six weeks for a newborn's antibody to rise in the serum after getting various antigenic stimuli2, while the process takes only one to two weeks in case of an adult.
However, his immune function develops rapidly after birth and he will be able to live moving forward without any problems in his ordinary life. A newborn must survive the neonatal period; he should not suffer from infections3.

High Antibody Titer Migrated to One's Baby

There are some ways and means for a newborn to survive without infections in his prenatal period, or some time before and after birth.
Firstly, there is a phenomenon called placental transmigration of antibody. The mother gives her immune antibody4 sufficiently to the fetus in her uterus; this protects her newborn from infection until he develops the immune function and becomes able to make antibodies on his own. The migrating antibody is IgG5, immunoglobulin (Ig) with a relatively small molecular weight. So the transmigrated antibody permeates among inside and outside of blood vessels as well as interstice to achieve its mission.
The mother is giving the antibody to her child against all kinds of infectivity factors that she had, particularly high antibody titer against bacteria and viruses experienced just prior to the delivery.


1: Immune function
Function to eliminate or process microbes and transplants that are recognized as "alien" by making antibody or owning to the presence of sensitized white blood cells like lymphocytes.

2: Antigenic stimulus
To stimulate the body immune system using antigen or antigenic substance. Antigen is a substance which induces an immune response by antibodies or cells. Bacteria, viruses and foreign proteins can be antigens.

3: Infection
When some parts of a human body are infected, host cells show specific responses to each pathogen. Infection is a disorder that produces clinical symptoms such as fever or pain.

4: Immune antibody
An antibody caused by immunity; immunogloblin in the serum that specifically responds to the antigen or immunogen. They sometimes adhere to the surface of lymphocyte for cellular immunity.

5: IgG immunoglobulin G
Immunogloblin with a molecular weight of 150,000, which occupies more than 80% of all the immunoglobins. They are bonded with bacteria, toxins and viruses and involved in the process of neutralization, sedimentation and coagulation.

Kobayashi, Noboru (1981). "Wagako wo Mamoru Hahaoya no Menekikotai"
(written in Japanese). Tokyo: Child Research Net. Retrieved Oct. 8, 2004, from the World Wide Web http://www.crn.or.jp/LIBRARY/KOBY/MIRAI/cbs0121.html
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